Cordycepin (3’-deoxyadenosine)
It has been shown that cordycepin is derived from the adenosine nucleoside. In vivo experiments have shown cordycepin to induce apoptosis of tumor cells in oral, breast, and colon cancer cell lines. Furthermore it has been shown to inhibit the TNF-α mediated invasion and migration of bladder cancer cells.
Cordycepic Acid (d-mannitol)
Cordycepic acid has the same chemical make-up as d-mannitol, and thus similar biological action. Cordycepic acid works in conjunction with cordycepin to preserve renal function and treat lung ailments. It has also been shown to have anti-aging and sleep-regulating effects.
Ergosterol
Ergosterol is a precursor of biologically important vitamin D2 and is found exclusively in mushrooms. Cordyceps sinensis fungus body contains a very high concentration of ergosterol (~11 mg/g). Whether or not it has any effect on body vitamin D levels is currently unknown. However it has been demonstrated by a number of studies to play a crucial role in reducing TNF-α mediated inflammation and having a cytotoxic effect against tumor cells in vitro.
Cordyceps Polysaccharides (CP)
A major constituent of the Cordyceps function carrying a diverse biological function. Cordyceps polysaccharides have demonstrates significant anti-tumor activity in mouse models as well as strong immunostimulatory action. It is generaly believed that major tumor-fighting properties of cordyceps are due to strong stimulation of the immune system.
